In order to allow the guardians to monitor the physiological parameters of the infant more intuitively and to be able to respond to sudden irregularities in the pulse rate, abnormal blood oxygen, high or low body temperature and other conditions, and to facilitate communication with the medical staff or to request assistance in treatment, an STM32 microcontroller-based infant health monitoring system is designed. The digital signal acquisition module for pulse, blood oxygen and body temperature acquire the raw data, and the microcontroller performs algorithmic processing to display the physiological parameters such as pulse, blood oxygen and body temper-ature of the infant, and configures the threshold alarms for the physiological parameters by means of a keypad module. Finally, the test results are compared and tested against the standard physiological parameters of infants and children to verify that the system meets the requirements of medical precision and accuracy.