Abstract: A double sided roll-to-roll (R2R) system has been developed by the authors to automate the continuous manufacturing of flexible display panels. Here we report an overview of the system operation and the fabrication process. The system framework features a timer initiated slot-die coating followed by wet lamination to form a thin, active layer in between flexible conductive substrates. A rotary screen-printing unit is installed for adhesive deposition providing an edge seal for the panel. The system enables production of 15-cm2 laminated panels.